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Posted at December 31, 1969, 6:00 pm: I would definitely be mindful of BCAA overconsumption and whey if you are battling depression/anxiety and be particulary cautious about valine and isovaline. In short, trytophan is the precursor for serotonin synthesis and BCAA's compete with tryptophan at the blood brain barrier for transport into the brain. All large nuetral amino acids (LNAAs) compete with one another for the same carrier complex. The bottom line is that the amount of serotonin produced is directly related to tryptophan:LNAA ratio. The problem with BCAA's is that they escape hepatic metabolism and end up in the plasma in far greater amounts than other AA's....particulary tryptophan. This partially explains the mood-enhancing effects of testosterone because T increases protein synthesis and decreases levels of essential AA's.....specifically all the LNAAs except tryptophan. Thus, after increases in T the tryptophan:LNAA ratio goes up followed by enhancement of mood. Original of the message was taken from http://forum.bodybuilding.com/ Previous Post: There are theories of "central fatigue" where BCAA supplemen... Next Post: Thanx for the detailed response The issue is I guess, that its hard t... |