Topic: Effects of glycine, glutamine and niacin on memory, GH and IGF-I secretion.

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Posted at July 29, 2018, 9:50 pm:

I just was flipping throu PubMed and I came across this study. Does anyone happen to have more info on this?

Effects of an oral mixture containing glycine, glutamine and niacin on memory, GH and IGF-I secretion in middle-aged and elderly subjects.

It is concluded that an oral mixture of glycine, glutamine and niacin can enhance GH secretion in healthy middle-aged and elderly subjects.

Arwert LI, Deijen JB, Drent ML.

Department of Endocrinology, VU University Medical Center, de Boelelaan 1117, 1081 HVAmsterdam, The Netherlands.

Aging is associated with declining activity of the growth hormone-insulin-like growth factor-I (GH-IGF-I) axis and with a decrease in cognitive function. The stimulatory effect of an orally administered nutritional supplement, mainly containing glycine, glutamine and niacin on the GH-IGF-I axis and on mood and cognition was investigated. Forty-two healthy subjects (14 men and 28 women, aged 40-76 years) were enrolled in a randomised, double blind, placebo-controlled trial. They received 5 g of a nutritional supplement or placebo, twice daily orally for a period of 3 weeks. At baseline and after 3 weeks, blood was collected for measurement of serum GH and IGF-I levels and mood and cognitive function were tested. The nutritional supplement ingestion for 3 weeks was found to increase serum GH levels with 70% relatively to placebo, whereas circulating IGF-I levels did not change. Mean GH (+/- SD) increased in this group from 3.23 (+/- 4.78) to 4.67 mU/l (+/- 5.27) (p = 0.03). GH increase was not associated with improvement in mood or memory. Correlation analyses, however, revealed that individual increases in IGF-I, but not GH, were associated with improved memory and vigour. It is concluded that an oral mixture of glycine, glutamine and niacin can enhance GH secretion in healthy middle-aged and elderly subjects.

Original of the message was taken from http://forum.bodybuilding.com/

Replies:

Probably won't help much, but I've read a few studies that have linked...

Nice posting

Nice Post

Good to know.

Now if only they would split up those 3 supplements to find out which ...

Glycine Glycine is a nonessential amino acid contained in gelatin pro...

Just for the sake of trivia.

Pricing info: Glutamine: $20 per 1000g Glycine: $17 per 1000g ...

I have been running this for almost 2 weeks.

Awesome.

Any updates ?

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So we should eat lots of Jello? :P It's wiggly, it's jiggly.

More research is needed.

O lol, I did not think anyone would be interested in this.

Awesome.

Thanks Billy and Pure, wish there were more threads like this on these...

niacin was shown only to increase gh if taken before heavy training, u...

References ?

In this study subjects taking 280 milligrams of niacin mixed with eith...

empty post

I ran across this article, which is not exactly related to the origina...

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